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A Sequence-Based Analysis of the Pointer Distribution of Ciliate Genes

Artiom Alhazov, Ion Petre, Sergey Verlan, A Sequence-Based Analysis of the Pointer Distribution of Ciliate Genes. TUCS Technical Reports 902, Turku Centre for Computer Science, 2008.

Abstract:

It has long been known that the lengths of some of the pointers in the
micronuclear ciliate genes are too short to allow for the unambiguous
recognition of their coding and noncoding blocks. Many of these pointers have
multiple occurrences along the gene, allowing for a very high number of
possible divisions into coding and noncoding blocks. We investigate in this
paper the pointer distribution of all currently sequenced micronuclear ciliate
genes with the goal of identifying what distinguishes the real gene structure
among all possible coding/noncoding divisions. We find a surprisingly sharp
criterium in the total AT percentage of the IESs of each such division: the
real gene has, in most cases, the maximum such percentage among all possible
combinations.

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BibTeX entry:

@TECHREPORT{tAlPeVe08a,
  title = {A Sequence-Based Analysis of the Pointer Distribution of Ciliate Genes},
  author = {Alhazov, Artiom and Petre, Ion and Verlan, Sergey},
  number = {902},
  series = {TUCS Technical Reports},
  publisher = {Turku Centre for Computer Science},
  year = {2008},
  keywords = {Ciliates, pointers, sequence analysis, pointer distribution},
}

Belongs to TUCS Research Unit(s): Computational Biomodeling Laboratory (Combio Lab)

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